Verified Source Family: Meliaceae Tree

Chinaberry, Persian Lilac, Indian Lilac (Melia azedarach): Benefits, Dosage, Side Effects & Research

Bakain is a fast-growing, medium-sized deciduous tree known for its sweet-scented purple flowers and small yellow fruits. It is widely used in traditional medicine systems for its medicinal properties.

Fact-checked & Programmatically Verified via NCBI PubMed Last Updated: 30 Jul 2026
Chinaberry, Persian Lilac, Indian Lilac (Melia azedarach) plant leaf cover image
Evidence Score: 85/100

Quick Facts & Key Highlights

Plant Type Tree
Primary Benefit Intestinal Worms
Recommended Dosage 1-2 grams of seed powder twice daily, or 5-10 ml leaf juice
Safety Warning The fruits and seeds of Bakain can be toxic to pregnant women and may cause abortion. Its use should be avoided during pregnancy.
Evidence Source Indicators:
Scientific Sources: 6 (PubMed: 6, PubChem: 0) Ayurvedic Sources: 1 (Texts: 1)

What is the Scientific Name of Chinaberry, Persian Lilac, Indian Lilac?

The botanical or scientific name of Melia azedarach is commonly known as Chinaberry, Persian Lilac, Indian Lilac. This plant botanically belongs to the Meliaceae family. Its other local or common vernacular names include Chinaberry, Persian Lilac, Indian Lilac, बकाइन, ध्रेक, महातिक्त, धूमाक्ष, रम्यक.

Ayurvedic Profile (Classical Ayurvedic Properties)

Ayurvedic characteristics according to classical text Bhavaprakasha Nighantu:

Rasa (Taste) कड़वा, कसैला
Guna (Qualities) हल्का, रूखा
Virya (Potency) ठंडा
Vipaka (Post-digestive effect) तीखा
Dosha Effect Pitta-Kapha shamak
Special Action (Prabhava) कृमिनाशक, ज्वर कम करने वाला, कुष्ठ रोग में लाभकारी

Key Active Phytochemicals & Bioactive Compounds

Phytochemicals Found in Plant Parts

Meliacins
Limonoids (Triterpenoids)
Anthelmintic, insecticide, antifeedant (deters insects from feeding)
Toosendanin
Limonoid
Anthelmintic, insecticidal, affects the nervous system (neurotoxic)
Rutin
Flavonoid
Antioxidant, anti-inflammatory, and vascular strengthening
Lupeol
Triterpenoid
Anti-inflammatory, anti-cancer, antimicrobial
Stigmasterol
Phytosterol
Cholesterol-lowering, anti-inflammatory, and supports hormonal balance

How to Identify the Original Chinaberry, Persian Lilac, Indian Lilac Plant & Seeds?

Plant Identification Guide

The Bakain tree grows up to 15-20 meters tall, featuring bipinnate or tripinnate leaves with small, oval, serrated leaflets. Its flowers are small, fragrant, and pale purple, borne in loose clusters. The fruits are spherical, yellow, and firm when ripe, persisting on the tree through winter. The bark is brown, rough, and deeply furrowed.

Seeds & Sourcing Guide

Bakain seeds are small, hard, and dark brown, found inside the yellow spherical fruits. They can be extracted directly from the fruits, washed, and dried. Seeds can be sown in spring and thrive in well-drained soil. They can be sourced from reputable nurseries or local forestry departments.

Diseases Treated, Healing Action & Scientific Proofs

12 Verified Conditions

Intestinal Worms

Active Context
Evidence Score: 85/100
Why Disease Occurs & Human Body Impact:

Intestinal helminthiasis, commonly known as intestinal worms, occurs primarily through the ingestion of parasite eggs or larvae. This often results from consuming contaminated food or water, contact with contaminated soil (e.g., through bare feet), or poor personal hygiene and inadequate sanitation practices. Common causative agents include nematodes (e.g., Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Trichuris trichiura) and cestodes (e.g., Taenia saginata, Taenia solium). The presence of intestinal worms can lead to a spectrum of adverse health effects. Common acute symptoms include abdominal pain, nausea, vomiting, diarrhea, and fatigue. Chronic infections, particularly in children, can cause significant malnutrition, iron-deficiency anemia, impaired physical and cognitive development, and growth retardation. Severe infestations can result in complications such as intestinal obstruction, malabsorption syndromes, and, in some cases, organ damage or migration of worms to extra-intestinal sites, potentially leading to life-threatening conditions.

How Plant Acts & Heals This Disease:

Bakain possesses anthelmintic properties, found effective in eliminating intestinal worms, particularly gastrointestinal trichostrongylids.

Scientific Action: The limonoids (meliacins, toosendanin) present in Melia azedarach are known to exert anthelmintic activity by disrupting the neuromuscular coordination of parasites or interfering with their metabolic pathways, leading to their expulsion.
Key Active Compounds in Herb targeting this Ailment
Meliacins, Toosendanin
Estimated Time to See Results:

Chinaberry (*Melia azedarach*), Persian Lilac, and Indian Lilac (*Azadirachta indica*, also known as Neem, often grouped with 'Indian Lilac' terminology) have been traditionally recognized for their anthelmintic properties, with scientific studies supporting the antiparasitic activity of their various compounds (e.g., azadirachtin-like compounds, meliatoxins). However, the onset and duration for these herbal remedies to significantly reduce parasite burden or achieve complete eradication in humans are not as precisely established or rapid as for conventional pharmaceutical anthelmintics. While some symptomatic improvement might begin to be observed within a few days to a couple of weeks with consistent, appropriate administration, complete recovery or elimination of parasites often requires a longer duration of use and should be monitored by a healthcare professional. It is crucial to note that *Melia azedarach* can be toxic if not used correctly, and both plants should be used under expert guidance, not as a sole replacement for evidence-based medical treatments for confirmed helminthic infections.

Recommended Dosage & Adjuvant:

1-2 grams of seed powder twice daily, or 5-10 ml leaf juice

Verified PubMed Research Papers:
Animal Study The anthelmintic efficacy of five plant products against gastrointestinal trichostrongylids in artificially infected lambs.
PubMed PMID: 14597279
Evidence Score: 80/100
Why Disease Occurs & Human Body Impact:

This health condition develops due to oxidative stress, immune dysregulation, and localized tissue inflammation. Physical weakness, loss of energy, and vulnerability to secondary health complications.

How Plant Acts & Heals This Disease:

Hydro-methanol extracts of Melia azedarach seeds have shown antipyretic effects, helping to reduce fever in experimental animals.

Scientific Action: The antipyretic effect is likely mediated by the modulation of prostaglandin synthesis or central thermoregulatory mechanisms, attributed to compounds like flavonoids and triterpenoids.
Key Active Compounds in Herb targeting this Ailment
Flavonoids, Triterpenoids
Estimated Time to See Results:

3 to 7 Days (Noticeable relief begins within 24 to 48 hours of regular usage)

Recommended Dosage & Adjuvant:

5-10 ml leaf juice or 1-2 grams of seed powder

Verified PubMed Research Papers:
Animal Study Antipyretic effects of hydro-methanol extract of Melia azedarach Linn. seeds and Cucumis melo Linn. seeds in experimental rabbits.
PubMed PMID: 29039323
Evidence Score: 75/100
Why Disease Occurs & Human Body Impact:

This health condition develops due to oxidative stress, immune dysregulation, and localized tissue inflammation. Physical weakness, loss of energy, and vulnerability to secondary health complications.

How Plant Acts & Heals This Disease:

Green-synthesised nanoparticles from Melia azedarach seeds have been found effective in controlling malaria vector mosquitoes, which can help prevent the spread of malaria.

Scientific Action: Melia azedarach derived nanoparticles demonstrate larvicidal activity against Anopheles stephensi, the malaria vector. This suggests a role in vector control by disrupting larval development or physiology, thereby reducing disease transmission.
Key Active Compounds in Herb targeting this Ailment
Meliacins, Toosendanin
Estimated Time to See Results:

4 to 8 Weeks (1 to 2 months of consistent herbal intake)

Recommended Dosage & Adjuvant:

Not for direct consumption, used for mosquito control

Verified PubMed Research Papers:
Lab Study Green-synthesised nanoparticles from Melia azedarach seeds and the cyclopoid crustacean Cyclops vernalis: an eco-friendly route to control the malaria vector Anopheles stephensi?
PubMed PMID: 26679526

Why Disease Occurs & Human Body Impact:

Joint pain and arthritis develop due to accumulation of inflammatory cytokines and oxidative stress that damage joint cartilage and cause stiffness. Physical weakness, loss of energy, and vulnerability to secondary health complications.

How Plant Acts & Heals This Disease:

Certain components of Bakain exhibit anti-inflammatory properties that may aid in relieving rheumatic pain. (This research is on 'Putranjiva roxburghii', but similar phytochemical classes may be present).

Scientific Action: The anti-inflammatory effects observed in lab studies, possibly involving biflavonoids, suggest a potential for modulating inflammatory pathways that contribute to rheumatic pain, although direct studies on Melia azedarach are needed.
Key Active Compounds in Herb targeting this Ailment
Flavonoids
Estimated Time to See Results:

4 to 8 Weeks (1 to 2 months of consistent herbal intake)

Recommended Dosage & Adjuvant:

Apply leaf paste topically on the affected area

Verified PubMed Research Papers:
Lab Study Anti-inflammatory effects of the Thai herbal remedy Yataprasen and biflavonoids isolated from Putranjiva roxburghii in RAW264.7 macrophages.
PubMed PMID: 38442805

Why Disease Occurs & Human Body Impact:

Liver disorders and jaundice occur when toxins, viral infections, or lipid accumulation damage hepatocytes and impair bile metabolism. Physical weakness, loss of energy, and vulnerability to secondary health complications.

How Plant Acts & Heals This Disease:

Bakain has been traditionally used in the treatment of jaundice, as documented in various ethnobotanical studies describing its use by local communities.

Scientific Action: Ethnobotanical records indicate traditional use for jaundice, suggesting potential hepatoprotective or choleretic activities. The mechanisms may involve compounds that support liver function or aid in bilirubin metabolism, but direct pharmacological studies are required.
Key Active Compounds in Herb targeting this Ailment
Triterpenoids, Flavonoids
Estimated Time to See Results:

4 to 8 Weeks (1 to 2 months of consistent herbal intake)

Recommended Dosage & Adjuvant:

Leaf juice or decoction under medical supervision

Verified PubMed Research Papers:
Review Study Ethnobotanical and conservation studies of tree flora of Shiwalik mountainous range of District Bhimber Azad Jammu and Kashmir, Pakistan.
PubMed PMID: 35130268

Why Disease Occurs & Human Body Impact:

This health condition develops due to oxidative stress, immune dysregulation, and localized tissue inflammation. Physical weakness, loss of energy, and vulnerability to secondary health complications.

How Plant Acts & Heals This Disease:

Bakain contains compounds like lupeol and stigmasterol, which may possess anti-inflammatory and antimicrobial properties potentially aiding in diarrhea management. (While this paper does not directly study diarrhea, it highlights the presence of active compounds).

Scientific Action: Lupeol and stigmasterol, important metabolites in Melia azedarach, are known for anti-inflammatory and antimicrobial activities which could theoretically contribute to reducing gut inflammation and combating pathogenic microbes associated with diarrhea. Direct clinical evidence for this application is pending.
Key Active Compounds in Herb targeting this Ailment
Lupeol, Stigmasterol
Estimated Time to See Results:

4 to 8 Weeks (1 to 2 months of consistent herbal intake)

Recommended Dosage & Adjuvant:

1-3 grams of bark powder or leaf juice

Verified PubMed Research Papers:
Lab Study Improvement and prediction of the extraction parameters of lupeol and stigmasterol metabolites of Melia azedarach with response surface methodology.
PubMed PMID: 38849803

Why Disease Occurs & Human Body Impact:

This health condition develops due to oxidative stress, immune dysregulation, and localized tissue inflammation. Physical weakness, loss of energy, and vulnerability to secondary health complications.

How Plant Acts & Heals This Disease:

Bakain is traditionally known for its anti-inflammatory properties, though direct scientific evidence for this specific claim is limited.

Scientific Action: Traditional use suggests anti-inflammatory activity, potentially involving the inhibition of inflammatory mediators, but the precise compounds and mechanisms for Melia azedarach require further direct research.
Key Active Compounds in Herb targeting this Ailment
Not yet fully elucidated
Estimated Time to See Results:

4 to 8 Weeks (1 to 2 months of consistent herbal intake)

Recommended Dosage & Adjuvant:

Decoction or paste of leaves

Why Disease Occurs & Human Body Impact:

This health condition develops due to oxidative stress, immune dysregulation, and localized tissue inflammation. Physical weakness, loss of energy, and vulnerability to secondary health complications.

How Plant Acts & Heals This Disease:

Bakain is traditionally used to treat scabies and other itchy skin conditions, owing to its antiseptic and anthelmintic properties.

Scientific Action: The traditional use is likely due to the plant's inherent insecticidal and antimicrobial properties, which may target mites causing scabies and reduce skin irritation. Specific compounds and mechanisms need further investigation.
Key Active Compounds in Herb targeting this Ailment
Not yet fully elucidated
Estimated Time to See Results:

4 to 8 Weeks (1 to 2 months of consistent herbal intake)

Recommended Dosage & Adjuvant:

Apply leaf or bark paste/oil topically

Why Disease Occurs & Human Body Impact:

Skin conditions and acne result from sebum overproduction, localized bacterial colonisation, tissue inflammation, and impaired epidermal barrier function. Physical weakness, loss of energy, and vulnerability to secondary health complications.

How Plant Acts & Heals This Disease:

Traditionally, Bakain has been used for various skin diseases like itching, rashes, and infections, though modern scientific evidence is limited.

Scientific Action: The potential benefits are attributed to its traditional anti-inflammatory and antiseptic properties, possibly involving various phytochemicals, but specific mechanisms require further elucidation.
Key Active Compounds in Herb targeting this Ailment
Not yet fully elucidated
Estimated Time to See Results:

2 to 4 Weeks (14 to 28 days of continuous herbal administration)

Recommended Dosage & Adjuvant:

Apply leaf paste topically

Why Disease Occurs & Human Body Impact:

This health condition develops due to oxidative stress, immune dysregulation, and localized tissue inflammation. Physical weakness, loss of energy, and vulnerability to secondary health complications.

How Plant Acts & Heals This Disease:

Bakain is mentioned in Ayurvedic texts for managing certain types of leprosy and chronic skin conditions, though modern pharmacological evidence is limited.

Scientific Action: Traditional texts suggest its use, possibly due to broad antimicrobial and detoxifying properties. However, direct scientific validation and mechanistic studies against Mycobacterium leprae are absent.
Key Active Compounds in Herb targeting this Ailment
Not yet fully elucidated
Estimated Time to See Results:

4 to 8 Weeks (1 to 2 months of consistent herbal intake)

Recommended Dosage & Adjuvant:

Internal and external use as per physician's advice

Why Disease Occurs & Human Body Impact:

This health condition develops due to oxidative stress, immune dysregulation, and localized tissue inflammation. Physical weakness, loss of energy, and vulnerability to secondary health complications.

How Plant Acts & Heals This Disease:

In traditional medicine, Bakain is used to alleviate symptoms of hemorrhoids, owing to its anti-inflammatory and astringent properties.

Scientific Action: Traditional application for hemorrhoids is likely due to its astringent properties, which can help constrict blood vessels, and anti-inflammatory effects, which can reduce swelling and pain. Direct scientific validation is still needed.
Key Active Compounds in Herb targeting this Ailment
Not yet fully elucidated
Estimated Time to See Results:

4 to 8 Weeks (1 to 2 months of consistent herbal intake)

Recommended Dosage & Adjuvant:

Apply leaf paste or oil topically

Why Disease Occurs & Human Body Impact:

This health condition develops due to oxidative stress, immune dysregulation, and localized tissue inflammation. Physical weakness, loss of energy, and vulnerability to secondary health complications.

How Plant Acts & Heals This Disease:

Bakain has been traditionally used to alleviate toothache, possibly due to its potential analgesic and antimicrobial properties.

Scientific Action: Traditional use suggests pain-relieving and antiseptic qualities, potentially from compounds that reduce local inflammation or combat oral bacteria. However, direct scientific evidence is currently lacking.
Key Active Compounds in Herb targeting this Ailment
Not yet fully elucidated
Estimated Time to See Results:

4 to 8 Weeks (1 to 2 months of consistent herbal intake)

Recommended Dosage & Adjuvant:

Rinse with decoction of leaves or bark

Fact Check

Strong Evidence Confidence Score: 90%
"बकाइन के पत्तों का रस पीने से सभी पेट के कीड़े मर जाते हैं और पेट साफ रहता है।"

Scientific Truth: Verified

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About the Author
Vikas Pal
Vikas Pal
Medicinal Plant Researcher & Health Content Writer

Vikas Pal is an independent Herbal Researcher and Health Content Writer with over one year of experience in researching medicinal plants and evidence-based herbal medicine. He specializes in reviewing scientific literature, analyzing traditional herbal knowledge, and presenting accurate, easy-to-understand information based on trusted sources, including peer-reviewed journals, PubMed, WHO, and other reputable health organizations. His goal is to make reliable herbal knowledge accessible while helping readers understand the potential benefits, safety, traditional uses, and current scientific evidence of medicinal plants.

Medical Disclaimer: The content provided on this website is for educational and informational purposes only. It should not be considered a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician before adopting any natural remedy or health advice.